Sonic booms from the fighter planes were heard across northern England, reports AirLive.
Avro RJ 85 as involved in the incident
Communication was re-established after seven minutes and the Cityjet plane was escorted to Newcastle airport.
"Quick reaction alert Typhoon aircraft were launched today from RAF Coningsby to identify an unresponsive civilian aircraft. Communications were re-established and the aircraft has been safely landed."
It is not known why the Cityjet plane changed course.
This follows a similar situation on April 30 when a British Airways 777 from Dubai to London Heathrow also went quiet over Hungary. Fighter jets from the central European country were scrambled but communication was re-established soon after.